Canderm-BG

Pharmaceutical name: Beclomethasone dipr./ Clotrimazole/ Gentamicyne

Betamethasone is a synthetic glucocorticoid, the most active of the anti-infalammatory steroids, used topically as an anti-infalmmatory and administered orally as a replacment therapy for adrenal insufficiency. Its derivative Betamethasone Dipropionate is a corticosteroid with mainly glucocorticocoid activity. It has slow but more prolonged actions. Betamethasone Dipropionate is used topically in the treatment of various skin disorders. Betamethasone Sodium Phosphate is a corticosteroid which is used topically or rectally as sodium phosphate as an antiinflammatory steroid. Betamethasone (Valerate) is the 17-valerate ester of betamethasone

Therapeutic actions:
Beclometasone is a synthetic corticosteroid and is used to decrease inflammation in the skin. When applied to the skin it is absorbed into the skin cells. Here it works by preventing the release of certain chemicals from the cells.

Clotrimazole is an antifungal medicine used to treat infections with fungi and yeasts. Clotrimazole kills fungi and yeasts by interfering with their cell membranes. It works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol causes holes to appear in the fungal cell membrane.
Gentamycine belongs to a class of antibiotics known as the aminoglycosides.
Gentamicine is bactericidal in action (kills bacteria). It does this by causing the bacteria to produce defective proteins which are essential for their growth.

Indications:
Canderm-BG is used to treat:
• Dermatomycosis ((Tinea's, Tinea ciuris, Tinea corporis) caused by Trichophyton rubrum, Trichophyton mentagrophyles, Epidermophyton floccosum, icrosporum canis and superficial skin candidosis.
• Area of thickened itchy skin caused by rubbing and scratching (lichen simplex)
• Eczema
• Inflammation of the skin
• Inflammatory skin disease known as discoid lupus erythematosus (DLE)
• Skin inflammation due to allergies or irritants (allergic or irritant dermatitis)
• Pyodermatosis
• Streptococcal impetigo

Contraindications and cautions:
Do not use Canderm-BG if you have an allergy to:
• any medicine containing beclometasone clotrimazole gentamycin
• any of the ingredients listed at the end of this leaflet (see Product description).
• any other similar medicine, that is, topical corticosteroids ,antibiotics ,antimycotics drugs

Do not use Canderm -BG in:
• tuberculosis (TB) or syphilis
• a virus such as chicken-pox or shingles
• a skin reaction following a vaccination
• Chronic inflammatory disorder of the facial skin (acne rosacea)
• Itching around the back passage and genitals
• Leg ulcers
• Children less than 1 year of age
Do not use Canderm-BG if you:
• are pregnant or plan to become pregnant.
• are breast-feeding or plan to breastfeed.

Warning!
• This preparation is for external use only.
• This medicine should be applied thinly and evenly to the affected area(s).
• This medicine should not be used for longer than five days on the face
• Use with caution in children

Adverse effects: Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Tell your doctor or pharmacist:
if you notice any of the following and they worry you:
• itching
• burning
• redness
The following list includes side effects that are rare:
• thinning of the skin
• the appearance of fine blood
• vessels on the skin surface
• stretch marks
• acne
• infection of hair follicles
• excessive unwanted hair growth
• redness and irritation around the mouth (perioral dermatitis)
• allergic skin reactions
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.