Methotrexate

Methotrexate 2.5mg is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis.  Methotrexate works by interfering with cell growth and by suppressing the immune system. Early treatment of rheumatoid arthritis with more aggressive therapy such as Methotrexate helps to reduce further joint damage and to preserve joint function.

For managing psoriasis or rheumatoid arthritis, take Methotrexate exactly as directed, usually once a week. It may take up to several months of continued use before the full benefit of Methotrexate takes effect. Do not increase your dose or take Methotrexate more often without your doctor's approval. Your condition will not improve any faster and the risk of serious side effects may be increased.

Unless your doctor instructs you otherwise, drink plenty of fluids while taking Methotrexate. This helps your kidneys to remove the drug from your body and minimize some of the side effects. Methotrexate may come with a Patient Information Leaflet. Read it carefully. Ask your doctor or pharmacist any questions that you may have about this medicine.

It is important to use each dose at the scheduled time. If you miss a dose of Methotrexate, contact your doctor or pharmacist immediately to establish a new dosing schedule.  Do not double the dose to catch up.

Side Effects
Nausea, vomiting, stomach pain, drowsiness or dizziness may occur.  If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed Methotrexate because he or she has judged that the benefit to you is greater than the risk of side effects.  Many people using Methotrexate do not have serious side effects.

Tell your doctor immediately if any of these serious side effects occur: mouth sores, diarrhea, fever, fatigue, persistent sore throat, unusual bleeding or bruising, black stools, skin rash, enlarged glands/lymph nodes, dark urine, bone pain, unusual pain and discoloration of the skin.