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Lamictal (Lamotrigine) is an anticonvulsant used alone or with other medicines to treat seizure disorders. Use of lamotrigine in children age 2 to 15 years of age is restricted to those having certain types of seizures (partial or Lennox-Gastaut type). Lamotrigine is also used in bipolar disorder to reduce the occurrence of mood problems. This medicine may be used to treat other conditions as determined by your doctor. Therapeutic actions: Lamictal contains the active ingredient Lamotrigine that belongs to anti epileptic substances. Lamotrigine works by decreasing the excessive electrical activity in people with epilepsy. The excessive electrical activity causes brain to become over-stimulated. This in its turn triggers seizures or fits. Lamotrigine reduces the pathological activity of the neurons and does not inhibit their function. It stabilizes the neuron's membrane by decreasing the transport of sodium inside the brain cells and also by blocking the excessive release of amino acids(especially glutamate). All of these helps to prevents seizures. What is it used for?: Lamotrigine is used to treat: • Epilepsy associated with generalized tonic-clonic seizures called grand mal epilepsy and partial seizures. • Type of severe childhood epilepsy (Lennox-Gastaut syndrome – type of severe childhood epilepsy. • Bipolar affective disorder • Trigeminal neuralgia related to severe pain in the lips, gums, cheek, chin or eye Contraindications and cautions: Do not use Lamictal in : • allergy or hypersensitivity to Lamotrigine • Pregnancy • Breastfeeding • Children Talk with your health care provider prior to taking Lamictal if you experience the following conditions: • Elderly age. • Liver disease (decreased liver function) • Kidney diseases ( kidney failure) • Parkinson's disease. • Heart disease • Blood disorders
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